Jennifer McClure, PhD, is director of Investigative Science at Kaiser Permanente Washington Health Research Institute (KPWHRI). She is also a senior investigator and clinical psychologist whose research focuses on developing new interventions to reduce people’s risk of chronic disease and cancer or help them better manage existing chronic disease through:
Much of Dr. McClure’s research emphasizes creating highly individualized behavioral treatments that can be disseminated on a population level, through health care systems and tobacco quitlines or directly to individuals via digital health tools, such as mobile health (mHealth) apps. Her goal is to design programs that are effective, convenient, engaging, and cost-effective, understanding that to make the leap from research to real world, interventions should meet these criteria.
Dr. McClure is best known for her research creating novel treatments for nicotine dependence, particularly interventions targeted to smokers who are ambivalent about quitting. These individuals may want to quit smoking some day, but are not yet ready to give up tobacco. Most smokers fall into this category, but few interventions are targeted to this important group. Her research has demonstrated the effectiveness of using proactive counseling and online interventions to motivate and support smoking cessation among ambivalent smokers. Her work has also shed light on the potential risks and benefits of using biological indicators of disease or disease risk to motivate quitting. Now she is developing two new mHealth apps to help ambivalent smokers kick the habit: one designed for anyone who smokes and one designed specifically for smokers living with HIV.
Dr. McClure’s collaborative research covers a range of topics from reducing sedentary behavior to comparing the effectiveness of various strategies for assessing and diagnosing high blood pressure.
In recognition of her scientific contributions, Dr. McClure was named a fellow in the Society of Behavioral Medicine (SBM) in 2013 and a fellow in the Society for Research on Nicotine and Tobacco in 2018. In 2019 she joined the faculty of the Kaiser Permanente Bernard J Tyson School of Medicine as a professor in Health Systems Science. Dr. McClure is also an affiliate professor of health services at the University of Washington School of Public Health and an affiliate investigator in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center. She currently serves as the Secretary and Treasurer of the Society for Research on Nicotine and Tobacco.
Tobacco cessation; pharmocogenomics of nicotine addiction; treatment adherence; population-based behavior interventions; health risk communications; oral health promotion; dietary change; physical activity promotion; informed decision-making; psychoneuroimmunology; HIV
Development of eHealth and mHealth intervention tools
Depression treatment and development of behavior change interventions for people with serious mental illness
Prevention and treatment
Heffner JL, Catz SL, Klasnja P, Tiffany B, McClure JB. Development of a mobile health intervention with personal experiments for smokers who are ambivalent about quitting: formative design and testing. JMIR Form Res. 2020;4(8):e21784. doi: 10.2196/21784. PubMed
Ashare RL, Bernstein SL, Schnoll R, Gross R, Catz SL, Cioe P, Crothers K, Hitsman B, Marhefka SL, McClure JB, Pacek LR, Vidrine DJ, Vilardaga R, Kaufman A, Edelman EJ. The United States National Cancer Institute’s coordinated research effort on tobacco use as a major cause of morbidity and mortality among people with HIV. Nicotine Tob Res. 2021 Jan 22;23(2):407-410. doi: 10.1093/ntr/ntaa155. PubMed
Rosenberg DE, Anderson ML, Renz A, Matson TE, Lee AK, Greenwood-Hickman MA, Arterburn DE, Gardiner PA, Kerr J, McClure JB. Reducing sitting time in obese older adults: the I-STAND randomized controlled trial. J Aging Phys Act. 2020 Jun 4:1-11. doi: 10.1123/japa.2019-0470. [Epub ahead of print]. PubMed
Watson NL, Heffner JL, Mull KE, McClure JB, Bricker JB. Which method of assessing depression and anxiety best predicts smoking cessation: screening instruments or self-reported conditions. Nicotine Tob Res. 2020 Jun 2. pii: ntaa099. doi: 10.1093/ntr/ntaa099. [Epub ahead of print]. PubMed
Grekin E, Beatty JE, McGoron L, Kugler KC, McClure JB, Pop DE, Ondersma SJ. Testing the efficacy of motivational strategies, empathic reflections, and lifelike features in a computerized intervention for alcohol use: a factorial trial. Psychol Addict Behav. 2019 Sep;33(6):511-519. doi: 10.1037/adb0000502. Epub 2019 Aug 22. PubMed
Pocobelli G, Ziebell R, Fujii M, Hutcheson KA, Chang S, McClure JB, Chubak J. Symptom burden in long-term survivors of head and neck cancer: patient-reported versus clinical data. EGEMS (Wash DC). 2019;7(1):25. doi: 10.5334/egems.271. PubMed
Heffner JL, Mull KE, Watson NL, McClure JB, Bricker JB. Long-term smoking cessation outcomes for sexual minority vs. non-minority smokers in a large randomized, controlled trial of two web-based interventions. Nicotine Tob Res. 2019 Jul 9. pii: 5530422. doi: 10.1093/ntr/ntz112. [Epub ahead of print]. PubMed
Watson NL, Heffner JL, Mull KE, McClure JB, Bricker JB. Comparing Treatment Acceptability and 12-Month Cessation Rates in Response to Web-Based Smoking Interventions Among Smokers Who Do and Do Not Screen Positive for Affective Disorders: Secondary Analysis. J Med Internet Res. 2019;21(6):e13500. doi: 10.2196/13500. PubMed
Matson TE, Anderson ML, Renz AD, Greenwood-Hickman MA, McClure JB, Rosenberg DE. Changes in self-reported health and psychosocial outcomes in older adults enrolled in sedentary behavior intervention study. Am J Health Promot. 2019 Apr 7:890117119841405. doi: 10.1177/0890117119841405. [Epub ahead of print]. PubMed
McClure JB, Anderson ML, Krakauer C, Blasi P, Bush T, Nelson J, Catz SL. Impact of a novel oral health promotion program on routine oral hygiene among socioeconomically disadvantaged smokers: results from a randomized semi-pragmatic trial. Transl Behav Med. 2019 Feb 12. pii: 5316179. doi: 10.1093/tbm/ibz009. [Epub ahead of print]. PubMed
Research led by KPWHRI’s Beverly Green, MD, MPH, finds that patients prefer at-home monitoring of blood pressure.
Dr. Jennifer McClure shares advice and resources for staying physically and emotionally well during the COVID-19 crisis, and beyond.
As Dr. Jennifer McClure completes the last of three innovative studies, she reflects on how the work began, the difference it may make, and what happens next.
Tobacco remains a public health priority. Dr. Jennifer McClure discusses her new findings comparing ’acceptance and commitment therapy’ to standard care.